NCE SI Subcutaneous Injection Analysis System
The NCE is Subcutaneous Injection Analysis serves as a testing device that imitates the changes and stress factors that biopharmaceuticals along with peptides and small molecule drugs face following subcutaneous administration. The device assesses drug release patterns in vivo through a method that reproduces drug dissolution together with permeation in extracellular matrices.
- Greatly save animal resources
- Speed up prescription development
- Reduce research costs
- Simple and reliable operating software
Key features
The inner chamber simulates the subcutaneous tissue environment, and the outer chamber simulates the systemic circulation environment.
Record the release behavior of the drug in real time through the camera to assist in judging the drug performance
Equipped with an external light source, it can record the changes in light intensity during the experiment and judge the sedimentation behavior of the drug in the extracellular matrix.
The drug concentration changes in the device are monitored in real time through optical fiber, making the test results more accurate.
Applications
Product application (experimental dosage forms): Simulate the dissolution and penetration of drugs under the skin by constructing an in vivo subcutaneous environment.
- Macromolecule biological preparations
- Peptide drugs
- Small molecule subcutaneous injections
Technical specifications
- Number of channels
- 3
- pH range
- 4~10
- Stirring rate
- 100~1000rpm
- Stirring accuracy
- ±10rpm
- Wavelength range
- 200~850nm
- Minimum acquisition time
- 1s
- Wavelength accuracy
- 1nm
- Temperature range
- room temperature~40℃
- Light source type
- deuterium lamp
- Light source life
- >1000h
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